Research

The evidence base.

Original papers, in-depth reviews of the literature, methods, and the field's landscape — the full evidence base of microbial metallomics.

Original Research

Papers from this group

Original preprints and articles developing the microbial-metallomics framework, published open-access on Zenodo.

Original ResearchPreprintJan 31, 2026

Six Decades of Fertilizer Use Built a Legacy of Cadmium, Nickel, and Lead in Soils and Diets

A food metallomics review (1960–2025) showing how phosphate and urea fertilizers loaded soils, crops, and diets with cadmium, nickel, lead, and chromium.

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Original ResearchPreprintJan 30, 2026

Heavy Metals and Microbial Metallomics: A New Framework for the US Obesity Epidemic

How dietary cadmium, arsenic, lead, and nickel may disrupt gut microbial metallomics—driving dysbiosis, inflammation, and insulin resistance behind obesity.

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Original ResearchPreprintJan 25, 2026

Developmental Readiness Is Not Toxicokinetic Safety: Heavy Metals in Vegetable-Based Baby Foods

Developmental readiness for solids does not ensure toxicokinetic safety: leafy greens, brassicas and root crops concentrate lead, cadmium and arsenic in baby foods.

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Original ResearchStandardJan 22, 2026

Concentration-Based Heavy Metal Standards to Reduce Real Exposure in Infant and Child Foods

HMTc 2026 sets concentration-based, as-sold action levels for lead, arsenic, cadmium, mercury, nickel and other heavy metals in infant and child foods.

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Original ResearchJournal articleJan 9, 2026

Nickel as a Catalytic Driver of Necrotizing Enterocolitis

Dietary nickel in infant formula may activate nickel-dependent microbial enzymes (urease, glyoxalase I) that drive necrotizing enterocolitis in preterm infants.

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Original ResearchJournal articleDec 29, 2025

A Unified Model for FIP-Associated Gingivitis in Cats: Disrupting Microbial Shielding and Restoring Nutritional Immunity

How itraconazole and lactoferrin may treat FIP-linked gingivitis in cats by disrupting polymicrobial biofilms and restoring metal-based nutritional immunity.

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Original ResearchJournalDec 27, 2025

Microbiome Medicine Journal: Restoring Causal Structure to Disease Through Microbial Metallomics

Microbiome Medicine Journal Vol. I sets out a mechanism-first framework linking microbial ecology, host metallome regulation, and metal dyshomeostasis to disease.

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Original ResearchJournal articleDec 27, 2025

From Dysbiosis to Dyshomeostasis: Reframing Parkinson's Through a Metallomic–Microbiome Lens

A metallomics framework reframes Parkinson's as metal dyshomeostasis: iron, manganese, copper, zinc and nickel dysregulation drives dysbiosis and neuron loss.

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Original ResearchJournal articleDec 18, 2025

The MC1R–Parkinson's Link May Be a Metallomic Story, Not a Cosmetic One

A hypothesis linking MC1R red-hair variants to Parkinson's risk via melanin-metal chemistry: how copper, zinc, and iron shape neuromelanin's redox buffering.

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Original ResearchJournal articleDec 5, 2025

Parkinson's Disease as a Disorder of Metal Dyshomeostasis Amplified by Microbial Ecology

A synthesis framework proposing Parkinson's disease begins with heavy-metal dyshomeostasis that drives ferroptosis, gut dysbiosis, and α-synuclein pathology.

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